5-Fluoro-2-methylphenylmagnesium bromide solution 0.5 in THF - Names and Identifiers
5-Fluoro-2-methylphenylmagnesium bromide solution 0.5 in THF - Physico-chemical Properties
Molecular Formula | C7H6BrFMg
|
Molar Mass | 213.33 |
Density | 0.960g/mLat 25°C |
Boling Point | 65°C |
Flash Point | 1°F |
Appearance | Solution |
Color | Clear yellow |
Storage Condition | 2-8°C |
Sensitive | Air & Moisture Sensitive |
5-Fluoro-2-methylphenylmagnesium bromide solution 0.5 in THF - Risk and Safety
Risk Codes | R11 - Highly Flammable
R14/15 -
R19 - May form explosive peroxides
R34 - Causes burns
R40 - Limited evidence of a carcinogenic effect
R36/37 - Irritating to eyes and respiratory system.
|
Safety Description | S16 - Keep away from sources of ignition.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S33 - Take precautionary measures against static discharges.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.)
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37 - Wear suitable protective clothing and gloves.
|
UN IDs | UN 2924 3/PG 2 |
WGK Germany | 1 |
HS Code | 29310099 |
Hazard Note | Flammable |
Hazard Class | 3 |
5-Fluoro-2-methylphenylmagnesium bromide solution 0.5 in THF - Introduction
bromide is an organic compound whose chemical formula is C7H7BrFMg. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: The bromide is a colorless to light yellow liquid.
-Solubility: Soluble in ethers and anhydrous ethanol, insoluble in water.
-Melting point and boiling point: no specific data.
Use:
-bromide is an important reagent, commonly used in the reaction of phenyl magnesium bromide in organic synthesis.
-This reagent can react with halides, ketones, esters, etc. to generate the corresponding organic magnesium compounds, which can then be used as nucleophilic reagents to participate in various organic synthesis reactions.
Preparation Method:
The preparation of the-bromide can be accomplished by the Grignard reagent method. First, a brominated compound (e. g., bromotoluene) is added to the magnesium dissolved in diethyl ether under an inert atmosphere. Then, the reaction is carried out by adding the corresponding fluoro compound (such as fluoroacetate) to form the bromide.
Safety Information:
-bromide belongs to organometallic reagents, with strong nucleophilicity and activity.
-During use and storage, care should be taken to avoid contact with air, water and oxygen to avoid dangerous reactions.
-Wear protective gloves and goggles during operation to ensure good indoor ventilation.
-Do not use it as a food or beverage ingredient, and avoid taking it by mistake or entering your eyes and skin.
-If accidentally touched or taken by mistake, flush immediately with plenty of water and seek medical assistance.
Last Update:2024-04-09 21:01:54